Accueil / hgd or africain 2012
(Agence Ecofin) - Le sud-africain AngloGold Ashanti, actif dans l'exploitation aurifère dans quatre pays africains ainsi qu'en Amérique latine, a publié le mardi 22 …
Plus de détailsPurpose We examined the microsatellite instability of duodenal tumors to evaluate their molecular features associated with the adenoma–carcinoma sequence. Methods Fifty-two non-ampullary duodenal epithelial tumors collected by endoscopic mucosal resection or surgical resection were studied. When a tumor had two or more …
Plus de détails2 Evidence 2.1 Systematic review evidence 2.1.1 Natural history of high-grade dysplasia 2.1.1.1 Non-resectable high grade dysplasia 2.1.1.2 Resectable polypoid high grade dysplasia 2.1.1.3 Resectable non-polypoid high grade dysplasia 2.1.1.4 Invisible dysplasia 2.1.2 Treatment of high grade dysplasia 2.1.3 Patient preferences
Plus de détails(Agence Ecofin) - En 2018, le Ghana a produit 158 tonnes d'or selon le « Commodity Markets Outlook» publié par la Banque mondiale le mois passé, soit une …
Plus de détailsBackground and Aim To verify the current status in Japan on endoscopic diagnosis of superficial non-ampullary duodenal epithelial tumors (SNADET) by a multicenter case series through a questionnair...
Plus de détailsTanaka M, Fernández-del Castillo C, Adsay V, et al. International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas. Pancreatology 12:183-197, 2012. PMID: 22687371; Tanno S, Nakano Y, Koizumi K, et al. Pancreatic ductal adenocarcinomas in long-term follow-up patients with branch duct intraductal papillary …
Plus de détailsTo interpret this literature, the reader should know that the indications for ESD differ between two countries: gastric adenomas with either low-grade dysplasia (LGD) or high-grade dysplasia (HGD) are usually endoscopically resected in Korea, whereas ESD is mostly reserved for early gastric cancers (EGCs) in Japan.
Plus de détailsIf cribriform architecture is defined as gland-in-gland configuration, the example in Figure 2(a) should be recognized as HGD while the example in Figure 2(b) may represent a borderline lesion, causing diagnostic discrepancy between LGD and HGD. Our results suggest that loss of nuclear polarity is the most reliable feature of HGD and …
Plus de détailsBy comparison, aneuploidy was detected in 14 of 15 samples with flat HGD (93.3%) and 2 of 45 samples that were negative for dysplasia (4.4%). The univariate hazard ratio for subsequent detection of HGD or colorectal cancer in patients with fLGD and aneuploidy was 5.3 (95% CI, 1.542−24.121) within a mean follow-up time of 37 months.
Plus de détailsIntroduction. Barrett's oesophagus (BO) is a premalignant condition which predisposes to oesophageal adenocarcinoma (OAC), an aggressive tumour with increasing incidence in the Western population over the past four decades. 1 Malignant progression of BO occurs in a stepwise manner through early neoplastic stages known as low-grade …
Plus de détailsMethods of identifying BE patients at high risk for progression to high-grade dysplasia (HGD) or EAC are needed to improve outcomes and identify who will benefit most from intensive surveillance...
Plus de détailsData for 2007–2012 from the German National Screening Colonoscopy Registry, including 594,614 adenomas identified during 2,532,298 screening colonoscopies, were analyzed retrospectively. The main outcome measure was the rate of high-grade dysplasia (HGD) in adenomas, used as a surrogate marker for the risk of malignancy.
Plus de détailsPatients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal advanced neoplasia, including colorectal high-grade dysplasia (HGD) and colorectal cancer (CRC).,,, Chronic intestinal inflammation is considered as a promoter of carcinogenesis.
Plus de détailsResults Average size of large polyps was 34.1 mm (range 20–150 mm, standard deviation 16.1 mm). Histology included 52.5 % adenomas with low-grade dysplasia (LGD), 26.7 % with high-grade dysplasia (HGD), 9.6 % serrated polyps and 11.2 % adenocarcinomas.
Plus de détailsIn this large Dutch nationwide population-based study focusing on the consistency of a diagnosis of HGD in BE, we showed that, after an initial HGD diagnosis, …
Plus de détailsResults A total of 148 patients underwent RFA, of whom 113 completed the treatment protocol (21 low-grade dysplasia (LGD), 46 high-grade dysplasia (HGD) and 46 intramucosal carcinoma (IMC)). CRD and CRIM were achieved in 94.7% and 78.8% of patients, respectively.
Plus de détailsL'Afrique du Sud, premier producteur d'or africain depuis des décennies, vient de perdre sa couronne et se place désormais au 3e rang africain et au 8e rang mondial. Voici le …
Plus de détailsfor HGD, and invasive carcinoma was detected in all (2 patients, T1 N0; 1 patient, T2 N0). Six patients had invasive carcinoma on endoscopic surveillance at a me-dian of 15 months (range, 3-34 months) after diagnosis of HGD and underwent endoscopic mucosal resection
Plus de détailsBackground & aims: Barrett's esophagus (BE) with high-grade dysplasia (HGD) or intramucosal carcinoma (IMC) is treated by complete eradication of areas of BE by endoscopic mucosal resection (EMR). By using this …
Plus de détailsCite Permissions Share Abstract To ascertain the prevalence of carcinoma in esophagi resected for high-grade dysplasia (HGD) using current criteria and to evaluate histologic features that may predict concurrent carcinoma, we studied specimens from 127 esophagectomies performed for HGD, or HGD "suspicious" for carcinoma (HGD/S) in …
Plus de détailsIntroduction. The early diagnosis of oesophageal adenocarcinoma is essential given its increasing incidence and the poor outcome for those with more advanced disease. 1 Early stage adenocarcinoma and its precursor, high grade dysplasia (HGD), are being identified more frequently as part of Barrett's surveillance programmes. 2 As experience …
Plus de détails1 Altmetric Metrics Abstract Background To date, the optimal management of patients with inflammatory bowel disease (IBD) and flat low-grade dysplasia (fLGD) of the colon or rectum remains controversial. Methods A systematic review was reported in accordance with PRISMA 2020 (Preferred Reporting Items for Systematic Reviews and …
Plus de détailsPolymerase chain reaction analysis of HPV DNA was performed on all 142 patients with esophageal lesions (38 HGD and 104 EAC). Thirty-seven patients (11 with HGD and 26 with EAC) had positive results for HPV DNA; 33 had HPV-16, 1 had HPV-18, and the remaining 3 had low-risk types 6 and 11. No multiple genotypes were detected in …
Plus de détailsHGD or with CIS for specific molecular analysis. This modern technology will permit translation of the histological structures of HGD or of CIS into molecular terms, in the future. In conclusion, it would appear that following the completion of chromosomal mutations in the nuclei of HGD-cells, their DNA, carrying the new genetic
Plus de détailsprior randomized, controlled trial demonstrated thatradiofrequency ablation (RFA) of Barrett's esophagus withhigh-grade dysplasia (HGD) was better than surveillance forthe outcome of progression to esophageal adenocarcinoma (N Engl J Med 2009;360:2277–2288).
Plus de détailsGastric dysplasia is a well-known precancerous lesion. Though the diagnosis of gastric low grade dysplasia (LGD) is generally made from endoscopic forceps biopsy (EFB), the accuracy is doubtful after numerous EFB-proven gastric LGD were upgraded to gastric high grade dysplasia (HGD) or even carcinoma (CA) by further diagnostic test …
Plus de détailsHypothesis:High-grade dysplasia (HGD) of the gas- tric epithelium is associated with high prevalence of in- vasivecarcinoma,anddistinctionbyendoscopicbiopsy is difficult. Design:Cohort study, 1996 to 2003. Setting:Tertiary care center. Patients:Consecutive sample of 22 patients with ini- tial diagnosis of gastric HGD by endoscopic biopsy.
Plus de détailsDifferentiating high-grade dysplasia (HGD) and T1 colorectal cancer (T1CRC) from low-grade dysplasia (LGD) in colorectal polyps can be challenging. Incorrect recognition of HGD or T1CRC foci can lead to a need for additional treatment after local resection, which might not have been necessary if it was recognized correctly.
Plus de détailsIntroduction. Incidence rate for adenocarcinoma of the small intestine is 6.8 per million. It is remarkably rare compared to other gastrointestinal carcinomas. 1 Reports on the distribution of adenocarcinomas in the small intestine vary with 47–58% found in the duodenum which is the most frequent site in the small intestine. 2-5 In the past two or …
Plus de détailsAbstract Background The introduction of endoscopic techniques has led to debate about optimal management of early oesophageal adenocarcinoma. The aim was to evaluate patient selection and outcomes for endoscopic or surgical treatment at a tertiary referral centre. Methods
Plus de détailsMalignant change in IPMN. IPMN is characterized by malignant transformation from low-grade dysplasia to high-grade dysplasia (HGD) and further to invasive carcinoma following adenoma-carcinoma sequence ().MD-IPMN is more frequently associated with this malignant transformation than is BD-IPMN (), necessitating surgical resection in more …
Plus de détails1 INTRODUCTION. Patients with ulcerative colitis or Crohn's disease colitis have an increased risk of colorectal cancer. The overall cancer prevalence was reported as 3.7% in the landmark meta-analysis by Eaden et al published in 2001. 1 The cumulative probabilities of developing cancer were reported to be 2% by 10 years, 8% by 20 years and 18% by …
Plus de détailsThis study aimed to evaluate risk factors for HGD/carcinoma that indicate a need for resection in biopsy-proven LGD lesions. Patients and methods: In total, 236 LGD lesions …
Plus de détailsResults Overall, 188 lesions with HGD/IMCA were included; 61 lesions were removed by en-bloc ER (e-ER), whereas 127 lesions were removed in a piecemeal ER (p-ER). The mean lesion size was 20.3 mm.
Plus de détails16 May 2012, and reviewed the major trends and policy developments in TVET since the Second International Congress held in Seoul, Republic of Korea, in 1999. We discussed …
Plus de détailsThere is an unclear risk of colonic high-grade dysplasia (HGD) and colorectal cancer (CRC) among patients with inflammatory bowel disease (IBD) treated with immunosuppressants. We analyzed data on CRC development among patients with IBD enrolled in the observational cohort Cancers et Surrisque Associé aux Maladies …
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